Circannual Biology: The Double Life of the Seasonal Thyrotroph
نویسنده
چکیده
Endogenous long-term timing is a key component of seasonality. Where and how are such rhythms generated? Recent findings pointed to the pituitary pars tuberalis, already implicated in photoperiod responsiveness. Now, a new study provides mechanistic insights which support this hypothesis.
منابع مشابه
Binary Switching of Calendar Cells in the Pituitary Defines the Phase of the Circannual Cycle in Mammals
Persistent free-running circannual (approximately year-long) rhythms have evolved in animals to regulate hormone cycles, drive metabolic rhythms (including hibernation), and time annual reproduction. Recent studies have defined the photoperiodic input to this rhythm, wherein melatonin acts on thyrotroph cells of the pituitary pars tuberalis (PT), leading to seasonal changes in the control of th...
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ورودعنوان ژورنال:
- Current Biology
دوره 25 شماره
صفحات -
تاریخ انتشار 2015